HASSIO is probably the easiest way to run Home Assistant. It's a pre-packaged appliance aimed at a few key devices such as Raspberry Pi and so on. Being an appliance has pros and cons. The primary con is that installing software and advanced system configuration is not possible, though this is conversely also the primary advantage! You spend time with Home Assistant not administrating the system.
Bad things happen and backups are your last line of defense in the event of hardware failure, theft